Matrix mineralization controls gene expression in osteoblastic cells
نویسندگان
چکیده
منابع مشابه
Genistein and zinc synergistically enhance gene expression and mineralization in osteoblastic MC3T3-E1 cells.
Genistein, a phytoestrogen, and zinc, an essential trace element, have an anabolic effect on bone components. We investigated whether the combination of genistein and zinc has additive and synergistic effects in osteoblastic cells in vitro. Osteoblastic MC3T3-E1 cells with subconfluency were cultured for 48 h in medium containing either vehicle, genistein (10(-6) or 10(-5) M), zinc sulfate (10(...
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Clinically, a decrease in blood pH may be due to either a reduction in bicarbonate concentration ([H[Formula: see text]], metabolic acidosis) or an increase in[Formula: see text] (respiratory acidosis). In mammals, metabolic acidosis induces a far greater increase in urine calcium excretion than respiratory acidosis. In cultured bone, metabolic acidosis induces a marked increase in calcium effl...
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ژورنال
عنوان ژورنال: Experimental Cell Research
سال: 2018
ISSN: 0014-4827
DOI: 10.1016/j.yexcr.2018.09.005